Description
PROPERTIES
| Quality Level | 200 |
| biological source | synthetic |
| form | powder |
| color | white to almost white |
| Mode of action | protein synthesis | interferes |
| antibiotic activity spectrum | Gram-negative bacteria mycobacteria |
| storage temp. | 2-8°C |
| SMILES string | O.NCC[C@H](O)C(=O)N[C@@H]1C[C@H](N)[C@@H](O[C@H]2O[C@H](CN)[C@@H](O)[C@H](O)[C@H]2O)[C@H](O)[C@H]1O[C@H]3O[C@H](CO)[C@@H](O)[C@H](N)[C@H]3O |
| InChI | 1S/C22H43N5O13.H2O/c23-2-1-8(29)20(36)27-7-3-6(25)18(39-22-16(34)15(33)13(31)9(4-24)37-22)17(35)19(7)40-21-14(32)11(26)12(30)10(5-28)38-21;/h6-19,21-22,28-35H,1-5,23-26H2,(H,27,36);1H2/t6-,7+,8-,9+,10+,11-,12+,13+,14+,15-,16+,17-,18+,19-,21+,22+;/m0./s1 |
| InChI key | DTSOZYYWEZJFSS-XTHCGPPUSA-N |
DESCRIPTION
General description
Chemical structure: aminoglycoside
Application
Amikacin hydrate is used in antimicrobial susceptibility studies of organisms such as Mycobacterium tuberculosis and Ehrlichia phagocytophila.
Biochem/physiol Actions
Amikacin inhibits bacterial protein synthesis by binding to the 30S ribosome subunit and inducing mRNA misreading. It interferes with the translocation of tRNA from the A-site to the P-site.
Packaging
5G
Other Notes
Keep container tightly closed in a dry and well-ventilated place.
SAFETY INFORMATION
Storage Class Code 11 – Combustible Solids
WGK WGK 2
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Personal Protective Equipment dust mask type N95 (US), Eyeshields, Gloves
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