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Antibiotic Antimycotic Solution (100×), Stabilized – A5955-100ML

5,361.30

Antibiotic Antimycotic Solution (100×), Stabilized – A5955-20ML

2,342.10

A5955 Sigma-Aldrich

Antibiotic Antimycotic Solution (100×), Stabilized

with 10,000 units penicillin, 10 mg streptomycin and 25 μg amphotericin B per mL, 0.1 μm filtered, BioReagent, suitable for cell culture

MDL number : MFCD00130520
NACRES : NA.76
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SKU: A5955-20ML Category:

Description

PROPERTIES

Quality Level 200
sterility 0.1 μm filtered
product line BioReagentc
form suspensiond
technique(s) cell culture | mammalian: suitable
impurities endotoxin, tested
color yellow
antibiotic activity spectrum Gram-negative bacteria
Gram-positive bacteria
fungi
yeast
application(s) agriculture
Mode of action cell wall synthesis | interferes
shipped in shipped in
storage temp. −20°C

DESCRIPTION

Application

This solution is formulated to contain 10,000 units penicillin, 10 mg streptomycin and 25μg Amphotericin B per mL, and is solubilized in a proprietary citrate buffer. It is recommended for use in cell culture applications at 10mL/L.
Antibiotic antimycotic solution has been used as a supplement in different types of cell culture media.

Biochem/physiol Actions

Mode of Action: Penicillin acts by inhibiting bacterial cell-wall synthesis. Streptomycin inhibits prokaryote protein synthesis by preventing the transition from initiation complex to chain-elongating ribosome and causes miscoding. Amphotericin B interferes with fungal membrane permeability by forming channels in the membranes and causing small molecules to leak out.

Antimicrobial spectrum: Includes Gram-negative bacteria, Gram-positive bacteria, fungi and yeasts.

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